Researchers at the Wake Forest University Center for Nanotechnology, in conjunction with researchers at Wake Forest University Health Sciences, have developed a novel coating for minimally invasive diagnostic measurements of pressure in medical devices. The implications of this technology are broad within the field of clinical medicine. Possible applications of the technology include:
• Acute or chronic compartment syndrome, a medical condition where trauma leads to a build of pressure in a closed space. This build up of pressure can create a devastating condition where blood flow to tissues is compromised and the tissue dies. Common places where compartment syndrome can occur are the leg, the forearm, and the abdomen.
• Intracerebral pressure (aka pressure build up surrounding the brain). Increased intracerebral pressure can lead to death if not treated immediately.
• Across valves in the heart. The pressure gradient across valves in the heart can be diagnostic of disease and life threatening cardiac disease.
• Aneurysm repairs. Aneurysms are the dilatation of the arterial vessel wall which can lead to rupture and death. After repairing aneurysm, a coating on endografts (sleeve used to repair an aneurysm) could be used to indicate a reoccurrence of the aneurysm.
• Radial artery pressure sensors. Radial artery pressure is used in the operating room and Intensive Care Unit (ICU) to indicate the "beat to beat" blood pressure of a patient. By using our technology as opposed to the current transducer model, a more accurate and less invasive device could be developed.
• Intrauterine pressure catheter (IUPC). Women in labor that is not progressing often have a pressure monitor placed to measure the strength of the uterine contractions as potential cause for a lack of progression. Our technology could be used to make a smaller device.
• Finally, anywhere in the body where monitoring pressure can be diagnostic of a patient's condition, this technology could supplant current technology due to its accuracy and minimal invasiveness.